Join us for an Exciting Webinar on Automating Protein LC-MS Sample Prep

Overview

Monoclonal antibodies are an important branch of new therapeutics that address many clinical indications. LC-MS plays a critical role in advancing monoclonal antibodies from discovery to development, identifying amino acids that can undergo modifications such as deamidation, cyclization, oxidation, and disulfide bond scrambling which can adversely impact biological activity. To arrive at one or two lead candidate sequences with the fewest sequence liabilities, dozens of peptide maps and glycan profile must be generated. The Andrew+ Robot powered by OneLab Software can significantly accelerate LC-MS workflow of monoclonal antibodies, eliminating tedious steps prone to human error.

Why Attend

·     Address key challenges that Analytical Chemists face when applying LC-MS to generate peptide maps and glycan profiles of biopharmaceuticals.

·     Learn the role that lab automation plays in terms of reducing tedious and error-prone sample preparation steps that are necessary prior to characterizing biopharmaceuticals by LC-MS.

·     How to leverage OneLab Software and the protocol library to develop LC-MS sample preparation methods for biopharmaceuticals that can be automated on the Andrew+ Robot.

Presented By

Ioannis Papayannopoulos, PhD
Principal, Analytical Biotechnology Consulting, LLC, Ashland, MA

Dr. Papayannopoulos has decades of experience with multiple facets of Analytical Protein Chemistry R&D, spanning basic discovery research to late-stage biopharmaceutical development at Biotechnology companies that have included Biogen, Astra Zeneca, Celldex Therapeutics, and Dragonfly Therapeutics.  He also served as Director of the Proteomics Core Facility at the MIT Koch Institute for Integrative Cancer Research.  Dr. Papayannopoulos graduated with a PhD in Organic Chemistry from the Massachusetts Institute of Technology (MIT) under the supervision of Prof. Klaus Biemann and an A.B in Chemistry from Bowdoin College. 

If you are unable to attend either of these sessions, you can still register to receive a link to watch the webinar on-demand after its initial broadcast.