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Watch Now: Learn how to Leverage a Next-Generation LC for Peptide Drug Substance Analysis

With skyrocketing demand for peptide-based treatments, and all eyes are on the QC bio lab. In this episode of the new LC Application Spotlight video series, meet your guide to improved flexibility, efficiency, and performance.

Episode 2: LC Application Spotlight, with Duanduan Han

Duanduan Han, Senior Scientist at Waters Corporation guides us through the analysis of insulin and GLP-1 peptides, sharing strategies to achieve outsized results with a bio-inert, biocompatible HPLC system built for large biomolecules.

 

Duanduan Han smiling

In this application, insulin and GLP-1 peptides are used to demonstrate the migration and modernization of reverse-phase liquid chromatography methods. The LC system's biocompatible alloy materials and titanium components increase resistance to corrosion from salt-containing buffers, ensuring long-term reliability.

You'll Learn:

§  How to improve accuracy in mobile phase composition

§  Enhance method robustness in QC environments, as evidenced by lower RSD in retention time

§  Improve performance in both isocratic and gradient methods, meeting compendial requirements for peptide fragment analysis

For more detailed information, please visit our website to access conference posters and application notes on this topic.

Watch the latest episode and read the full Application Note

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