Speeding up method development - How Cyprotex have solved the analytical challenge of non-specific binding

On Demand Webinar

Overview

An ongoing challenge when dealing with chromatographic separation is the presence of compounds that exhibit non-specific binding. Such compounds can exhibit poor peak shape, carryover, low sensitivity and cause an increase in back pressure and system clogging.

In this webinar, Cyprotex demonstrates how the ACQUITY Premier column and system with MaxPeak High Performance Surfaces (HPS) technology can address the challenge of non-specific binding in carrying out compound screening of small molecule and peptide pharmaceuticals in drug discovery.

The benefits of this new technology include increased sensitivity, improved peak shape and reduced carryover while eliminating non-specific binding.

This webinar covers:

§  The application of MaxPeak HPS technology for enhanced chromatographic performance of pharmaceutical compounds in UPLC-MS

§  The comparison of chromatographic performances of traditional stainless steel UPLC technology and the ACQUITY Premier solution

§  Significantly reducing method development turnaround

§  Minimizing non-specific binding

§  Eliminating a passivation requirement