WATERS Webinar: From Aggregation to Impurity Profiling: Analytical Best Practices for GLP-1RAs
Upcoming webinar:
From Aggregation to Impurity Profiling: Analytical Best Practices for GLP-1RAs
Tuesday, September 16
18:00 Greek Time
Overview
As GLP-1 receptor agonists (GLP-1RAs) continue to transform the treatment landscape for metabolic disorders, ensuring the integrity and quality of these complex molecules is more critical than ever. This webinar explores advanced analytical strategies for characterizing critical quality attributes (CQAs), with a focus on size-exclusion chromatography with multi-angle light scattering (SEC-MALS) and reversed-phase chromatography with mass spectrometry (RPC-MS).
Attendees will gain insights into SEC column selection for impurity profiling, the use of native vs. denaturing SEC for aggregation analysis, and the comparative strengths of MALS and MS detection. The session also features a side-by-side analysis of liraglutide and semaglutide, demonstrating how integrated data workflows using Empower CDS with MALS streamline complex analyses while supporting compliance requirements and product quality. Whether you're developing or monitoring GLP-1RAs, this session offers practical guidance and best practices using Waters end-to-end LC, column, detector, and software solutions.
Why Attend
- Understand critical quality attributes (CQAs) for GLP-1 receptor agonists
- Explore column selection strategies for SEC and RPC
- Compare MALS and MS detection techniques for aggregation and purity analysis
- Learn how Empower CDS supports compliance-ready, unified data workflows
Presented By
Bill Warren
Principal Product Manager
Waters Corporation
Bill Warren is Principal Product Marketing Manager within Waters Consumables and Automation Group. Over his 36-year tenure at Waters, he has developed various biomolecule applications and has helped manage a comprehensive line of bioseparation consumables for DNA/RNA, amino acid, peptide, protein, and glycan applications. His current focus is on chemistry consumables for proteins, DNA/RNA, and cell therapy-related applications.
Neil J. Lander
Principal Product Manager
Waters Corporation
Neil has worked for Waters Corporation since 1994 and currently serves as a Principal Product Manager in the Informatics group. Neil provides support for Empower CDS software and is focused on developing laboratory software solutions that help organizations achieve their scientific and operational objectives. Prior to joining Waters Corporation, he was an analytical chemist where he gained experience in both the cosmetics and specialty chemical industries.
If you are unable to attend either of these sessions, you can still register to receive a link to watch the webinar on-demand after its initial broadcast.