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6 OCTOBER 2025

Waters: New HFIP for LC-MS Workflows

Ultra-Pure. High-Performance. Ready to Elevate your LC-MS Results.

Ready to ship on Waters.com

Waters offers LC-MS Grade HFIP, purpose-built for Oligonucleotide LC-MS workflows. This new solution delivers the purity, performance, and convenience your lab demands, available exclusively online in two flexible volumes.

Why choose Waters IonHance HFIP?

  • Ultra-Pure Quality: <100 ppb sodium/potassium for cleaner MS spectra with reduced adducts 
  • Enhanced Performance: Improves ionization and sensitivity in ion-pair reversed-phase LC-MS
  • Convenient Sizing: Choose 10 mL or new 100 mL bottles to match your lab’s needs

Whether you're optimizing a method or scaling production, Waters HFIP is the ready-to-order solution that helps you get more from every run.

Shop HFIP Now

You may also be interested in:  Small Molecule Columns  |  Sample Prep and Vials  |  Bioseparation Consumables

Waters is now phasing out paper certificates of analysis (COAs) and chromatograms from consumable shipments. You can access your documents anytime by scanning the QR code on your product packaging, visiting the Certificates of Analysis page, or reading more in our notification document.