Upcoming Waters Webinar: CQA Assessment of GLP-1 RAs with SEC-MALS
Register Today - CQA Assessment of GLP-1 Agonist with SEC-MALS
Wednesday, October 15
16:00 Greek Time
Overview
Characterizing GLP-1 receptor agonists (GLP-1RAs), now central to diabetes and weight management therapies, demands precise and reliable analytical methods across development, manufacturing, and quality control. This webinar explores how light scattering techniques—including dynamic light scattering (DLS) and multi-angle light scattering (MALS)—enable detailed assessment of critical quality attributes (CQAs). With a particular focus on MALS coupled to size-exclusion chromatography (SEC-MALS) under native and denaturing conditions, attendees will learn how these approaches provide robust, quantitative insights into molar mass, size, aggregation, and oligomeric state, as well as their impact on colloidal stability.
Case studies will showcase the characterization of GLP-1 analogs—including liraglutide, semaglutide, and related peptides—highlighting applications like aggregation screening, impurity profiling, and stability analysis. The session will also discuss how the latest iteration of Empower™ Chromatography Data System integrates advanced detectors for orthogonal characterization in QC workflows, delivering secure, compliant data handling to support product integrity and regulatory readiness.
Why Attend
- Understand GLP-1 analogs: Learn about the biological functions and therapeutic importance of GLP-1 analogs in treating obesity and type-II diabetes
- Learn advanced analytical techniques: Gain knowledge on advanced light scattering for characterizing peptide drugs in the detection of aggregates, oligomeric states and peak heterogeneity
- Benefit from real-world applications: Explore actual case studies of light scattering techniques in assessing the quality and stability of GLP-1RA drugs
- Transfer to your lab: Learn what columns and conditions are required for ideal results and conditions for your own studies
Presented By
Udayabagya (Bud) Halim
Senior Marketing Analyst
Waters | Wyatt Technology
Bud Halim is a Senior Marketing Analyst at Wyatt Technology, bringing a wealth of scientific expertise to the analytical instrumentation field. He earned both his B.S. and Ph.D. in Physical Chemistry from UCLA, where he first developed his passion for science. Bud began his career in academia as an adjunct professor, teaching Biochemistry, Analytical Chemistry, and Physical Chemistry, while also contributing as an editor and author to several laboratory manuals. He later transitioned into the scientific instrumentation industry, serving in roles such as applications scientist, where he gained hands-on experience in the characterization of peptides, traditional biologics, lipid nanoparticles (LNPs), and viral vectors.
If you are unable to attend this session, you can still register to receive a link to watch the webinar on-demand after its initial broadcast.